Architecture of a channel-forming O-antigen polysaccharide ABC transporter

Nature64.80
Volume: 553, Issue: 7688, Pages: 361 - 365
Published: Jan 1, 2018
Abstract
O-antigens are cell surface polysaccharides of many Gram-negative pathogens that aid in escaping innate immune responses. A widespread O-antigen biosynthesis mechanism involves the synthesis of the lipid-anchored polymer on the cytosolic face of the inner membrane, followed by transport to the periplasmic side where it is ligated to the lipid A core to complete a lipopolysaccharide molecule. In this pathway, transport to the periplasm is...
Paper Details
Title
Architecture of a channel-forming O-antigen polysaccharide ABC transporter
Published Date
Jan 1, 2018
Journal
Volume
553
Issue
7688
Pages
361 - 365
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