Gold nanourchins and celastrol reorganize the nucleo- and cytoskeleton of glioblastoma cells

Gold nanourchins (AuNUs) associate with lysosomes and lipid droplets (LDs) in glioblastoma cells. AuNUs reorganize F-actin, microtubules and the nuclear lamina. This alters cell signaling and increases cell death. Cell injury is further enhanced by...