Preparation, characterization, and cellular uptake of resveratrol-loaded trimethyl chitosan nanoparticles
Abstract
The aim of the study was to encapsulate resveratrol (RV) in trimethyl chitosan (TMC) nanoparticles cross-linked with tripolyphosphate (TPP) and/or alginate to achieve controlled release and improved cellular uptake. TMC (degree of quaternization of 78%) was prepared by reacting purified chitosan with iodomethane. Three types of RV-loaded TMC nanoparticles were prepared: TMC-TPP (TP-NPs), TMC-alginate (TA-NPs), and TMC-alginate-TPP (TAP-NPs)....
Paper Details
Title
Preparation, characterization, and cellular uptake of resveratrol-loaded trimethyl chitosan nanoparticles
Published Date
Dec 13, 2017
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