Modeling of non-Fickian diffusion and dissolution from a thin polymeric coating: An application to drug-eluting stents

Volume: 114, Issue: 3, Pages: 292 - 320
Published: Feb 2, 2018
Abstract
Summary In this paper, we present a general model for non‐Fickian diffusion and drug dissolution from a controlled drug delivery device coated with a thin polymeric layer. First, we study the stability and deduce an analytic solution to the problem. Then, we consider this solution and provide suitable boundary conditions to replace the problem of mass transport in the coating of a coronary drug‐eluting stent. With this approach, we reduced the...
Paper Details
Title
Modeling of non-Fickian diffusion and dissolution from a thin polymeric coating: An application to drug-eluting stents
Published Date
Feb 2, 2018
Volume
114
Issue
3
Pages
292 - 320
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