Centchroman regulates breast cancer angiogenesis via inhibition of HIF-1α/VEGFR2 signalling axis
Abstract
Angiogenesis is a recognized hallmark of cancer which promotes cancer cell progression and metastasis. Inhibition of angiogenesis to attenuate cancer growth is becoming desirable strategy for breast cancer management. The present study is aimed to investigate the antiangiogenic efficacy of a novel selective estrogen receptor modulator Centchroman (CC) on human breast cancer cells. Effect of CC on cell viability was evaluated using Sulforhodamine...
Paper Details
Title
Centchroman regulates breast cancer angiogenesis via inhibition of HIF-1α/VEGFR2 signalling axis
Published Date
Jan 1, 2018
Journal
Volume
193
Pages
9 - 19
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