Review paper
The potential role of leptin in tumor invasion and metastasis
Abstract
The adipocyte-released hormone-like cytokine/adipokine leptin behaves differently in obesity compared to its functions in the normal healthy state. In obese individuals, elevated leptin levels act as a pro-inflammatory adipokine and are associated with certain types of cancers. Further, a growing body of evidence suggests that higher circulating leptin concentrations and/or elevated expression of leptin receptors (Ob-R) in tumors may be poor...
Paper Details
Title
The potential role of leptin in tumor invasion and metastasis
Published Date
Dec 1, 2017
Volume
38
Pages
80 - 97
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