Original paper
Cell-free DNA (cfDNA) mutations from clonal hematopoiesis: Implications for interpretation of liquid biopsy tests.
Volume: 35, Issue: 15_suppl, Pages: 11526 - 11526
Published: May 20, 2017
Abstract
11526 Background: A large fraction of cfDNA fragments are derived from hematopoietic sources. Somatic alterations in cfDNA can be tumor-derived but also could represent somatic changes associated with clonal hematopoiesis. We performed deep sequencing of both plasma cfDNA and matched white blood cell (WBC) genomic DNA (gDNA) to determine the contribution of clonal hematopoiesis to the variants observed in cfDNA. Four cohorts were investigated:...
Paper Details
Title
Cell-free DNA (cfDNA) mutations from clonal hematopoiesis: Implications for interpretation of liquid biopsy tests.
Published Date
May 20, 2017
Journal
Volume
35
Issue
15_suppl
Pages
11526 - 11526
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Notes
History