Other
Unravelling biology and shifting paradigms in cancer with single-cell sequencing
Abstract
In this Opinion article, Baslan and Hicks discuss how single-cell sequencing could be used to advance our understanding of tumour biology and genetics, in addition to translational applications in the clinic. The fundamental operative unit of a cancer is the genetically and epigenetically innovative single cell. Whether proliferating or quiescent, in the primary tumour mass or disseminated elsewhere, single cells govern the parameters that...
Paper Details
Title
Unravelling biology and shifting paradigms in cancer with single-cell sequencing
Published Date
Aug 24, 2017
Journal
Volume
17
Issue
9
Pages
557 - 569