Abstract 1206: miR-205 replenishment in prostate cancer cells: A novel nanoparticle approach

Introduction Prostate cancer (PrCa) is the most common male malignancy among men in the United States. Recent studies suggest that low expression of miR-205 is seen in PrCa cell lines and tumors in comparison to normal prostatic epithelial cells. A numer of studies have shown that restoration of miR-205 in PrCa cells resulted in supression of cell growth, epithelial-to-mesenchymal transition, and chemosensitization. However, due to the poor...