Anatomical brain difference of subthreshold depression in young and middle-aged individuals

Subthreshold depression (StD) is associated with substantial functional impairments due to depressive symptoms that do not fully meet the diagnosis of major depressive disorder (MDD). Its high incidence in the general population and debilitating symptoms has recently put it at the forefront of mood disorder research.In this study we investigated common volumetric brain changes in both young and middle-aged StD patients.Two cohorts of StD...