NeuroImage: Clinical
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4.88
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#1Michael S. Stringer (University of Edinburgh)H-Index: 4
#2Anna K. Heye (University of Edinburgh)H-Index: 8
Last. Joanna M. Wardlaw (University of Edinburgh)H-Index: 133
view all 9 authors...
Abstract null null Subtle blood-brain barrier (BBB) permeability increases have been shown in small vessel disease (SVD) using various analysis methods. Following recent consensus recommendations, we used Patlak tracer kinetic analysis, considered optimal in low permeability states, to quantify permeability-surface area product (PS), a BBB leakage estimate, and blood plasma volume (vP) in 201 patients with SVD who underwent dynamic contrast-enhanced MRI scans. We ran multivariable regression mod...
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#1Akifumi Hagiwara (UCLA: University of California, Los Angeles)H-Index: 3
#2Jingwen Yao (UCLA: University of California, Los Angeles)H-Index: 9
Last. Benjamin M. EllingsonH-Index: 56
view all 20 authors...
Abstract null null Purpose null To quantify abnormal metabolism of diffuse gliomas using “aerobic glycolytic imaging” and investigate its biological correlation. null null null Methods null All subjects underwent a pH-weighted amine chemical exchange saturation transfer spin-and-gradient-echo echoplanar imaging (CEST-SAGE-EPI) and dynamic susceptibility contrast perfusion MRI. Relative oxygen extraction fraction (rOEF) was estimated as the ratio of reversible transverse relaxation rate R2′ to no...
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#1Eva Hilland (UiO: University of Oslo)H-Index: 9
#2Cecilie Haggag Johannessen (UiO: University of Oslo)H-Index: 3
Last. Ingrid Agartz (UiO: University of Oslo)H-Index: 82
view all 17 authors...
Abstract null null Abnormal default mode network (DMN) connectivity has been found in schizophrenia and other psychotic disorders. However, there are limited studies on early onset psychosis (EOP), and their results show lack of agreement. Here, we investigated within - network null DMN null connectivity in EOP compared to healthy controls (HC), and its relationship to clinical characteristics. null A sample of 68 adolescent patients with EOP (mean age 16.53 ± 1.12 [SD] years, females 66%) and 9...
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#1Huichun Luo (SJTU: Shanghai Jiao Tong University)H-Index: 3
#1Luo Huichun (SJTU: Shanghai Jiao Tong University)
Last. Shouyan Wang (MOE: Ministry of Education of the People's Republic of China)
view all 6 authors...
Abstract null null The periventricular/periaqueductal gray (PAG/PVG) is critical for pain perception and is associated with the emotional feelings caused by pain. However, the electrophysiological characteristics of the PAG/PVG have been little investigated in humans with chronic pain. The present study analyzed the oscillatory characteristics of local field potentials (LFPs) in the PAG/PVG of eighteen neuropathic pain patients. Power spectrum analysis and neural state analysis were applied to t...
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#1Ali Kassab (University of Montreal)H-Index: 4
#2Dènahin Hinnoutondji Toffa (University of Montreal)H-Index: 3
Last. Dang Khoa Nguyen (University of Montreal)H-Index: 30
view all 6 authors...
Functional near-infrared spectroscopy (fNIRS) is currently the only non-invasive method allowing for continuous long-term assessment of cerebral hemodynamic. We evaluate the feasibility of using continueous electroencephalgraphy (cEEG)-fNIRS to study the cortical hemodynamic associated with status epilepticus (SE), burst suppression (BS) and periodic discharges (PDs). Eleven adult comatose patients admitted to the neuroICU for SE were recruited, and cEEG-fNIRS monitoring was performed to measure...
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#1Cheng Zhou (ZJU: Zhejiang University)H-Index: 7
#2Tao Guo (ZJU: Zhejiang University)H-Index: 8
Last. Min Xuan (ZJU: Zhejiang University)H-Index: 16
view all 14 authors...
Abstract null null Degeneration of the locus coeruleus (LC) is recognized as a critical hallmark of Parkinson's disease (PD). Recent studies have reported that noradrenaline produced from the LC has critical effects on brain functional organization. However, it is unknown if LC degeneration in PD contributes to cognitive/motor manifestations through modulating brain functional organization. This study enrolled 94 PD patients and 68 healthy controls, and LC integrity was measured using the contra...
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#1Ge Xiong (CSU: Central South University)H-Index: 4
#2Daifeng Dong (CSU: Central South University)H-Index: 9
Last. Haofei Zhao (CSU: Central South University)H-Index: 3
view all 12 authors...
Abstract null null It has been proposed recently that major depressive disorder (MDD) could represent an adaptation to conserve energy after the perceived loss of an investment in a vital source, such as group identity, personal assets, or relationships. Energy conserving behaviors associated with MDD may form a persistent marker in brain regions and networks involved in cognition and emotion regulation. In this study, we examined whether subcortical regions and volume-based structural covarianc...
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#1Arthur P C Spencer (University of Bristol)H-Index: 1
#2Jonathan C W Brooks (UEA: University of East Anglia)H-Index: 35
Last. Elavazhagan Chakkarapani (University Hospitals Bristol NHS Foundation Trust)
view all 10 authors...
Therapeutic hypothermia reduces the incidence of severe motor disability, such as cerebral palsy, following neonatal hypoxic-ischaemic encephalopathy. However, cooled children without cerebral palsy at school-age demonstrate motor deficits and altered white matter connectivity. In this study, we used diffusion-weighted imaging to investigate the relationship between white matter connectivity and motor performance, measured using the Movement Assessment Battery for Children-2, in children aged 6–...
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#1Modak P (IU: Indiana University)
#2Hutslar C (IU: Indiana University)
Last. Joshua W. Brown (IU: Indiana University)H-Index: 37
view all 10 authors...
Abstract null null Substantial effort has gone into neuroimaging studies of neural mechanisms underlying addiction. Human studies of smoking typically either give monetary reward during an fMRI task or else allow subjects to smoke outside the scanner, after the session. This raises a fundamental issue of construct validity, as it is unclear whether the same neural mechanisms process decisions about nicotine that process decisions about money. To address this, we developed a novel MR-compatible n...
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#1Elisa Guma (McGill University)H-Index: 8
#2Emily Snook (University of Toronto)H-Index: 4
Last. M. Mallar ChakravartyH-Index: 69
view all 7 authors...
Abstract null null Prenatal exposure to maternal immune activation (MIA) is a risk factor for a variety of neurodevelopmental and psychiatric disorders. The timing of MIA-exposure has been shown to affect adolescent and adult offspring neurodevelopment, however, less is known about these effects in the neonatal period. To better understand the impact of MIA-exposure on neonatal brain development in a mouse model, we first assess neonate communicative abilities with the ultrasonic vocalization ta...
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