Beta2-adrenergic signaling affects the phenotype of human cardiac progenitor cells through EMT modulation
Abstract
Human cardiac progenitor cells (CPCs) offer great promises to cardiac cell therapy for heart failure. Many in vivo studies have shown their therapeutic benefits, paving the way for clinical translation. The 3D model of cardiospheres (CSs) represents a unique niche-like in vitro microenvironment, which includes CPCs and supporting cells. CSs have been shown to form through a process mediated by epithelial-to-mesenchymal transition (EMT)....
Paper Details
Title
Beta2-adrenergic signaling affects the phenotype of human cardiac progenitor cells through EMT modulation
Published Date
Jan 1, 2018
Journal
Volume
127
Pages
41 - 48
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