Original paper
Abstract 1433: CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression
Abstract
The epithelial-mesenchymal transition (EMT) confers mesenchymal properties on epithelial cells and has been closely associated with the acquisition of aggressive traits by epithelial cancer cells. To identify novel regulators of EMT, we carried out cDNA screens that covered 500 human kinases. Subsequent characterization of candidate kinases led us to uncover cyclin-dependent kinase-like 2 (CDKL2) as a novel potent promoter for EMT and breast...
Paper Details
Title
Abstract 1433: CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression
Published Date
Aug 1, 2015
Journal
Volume
75
Issue
15_Supplement
Pages
1433 - 1433
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Notes
History