Review paper
Xenoestrogen regulation of ERα/ERβ balance in hormone-associated cancers
Abstract
The hormone 17β-estradiol (E2) contributes to body homeostasis maintenance by regulating many different physiological functions in both male and female organs. E2 actions in reproductive and non-reproductive tissues rely on a complex net of nuclear and extra-nuclear signal transduction pathways triggered by at least two estrogen receptor subtypes (ERα and ERβ). Consequently, the de-regulation of E2:ER signaling contributes to the pathogenesis of...
Paper Details
Title
Xenoestrogen regulation of ERα/ERβ balance in hormone-associated cancers
Published Date
Dec 1, 2017
Volume
457
Pages
3 - 12
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