Mineralocorticoid receptor as a therapeutic target in chronic kidney disease and hypertension
Abstract
The kidney has a central role in long-term control of blood pressure, and decreased kidney function is a common but difficult-to-treat cause of hypertension. Conversely, elevated blood pressure contributes to the progression of chronic kidney disease. Steroid hormone aldosterone and its receptor mineralocorticoid receptor (MR) contribute to hypertension by increasing renal salt reabsorption and promote kidney dysfunction through direct effects...
Paper Details
Title
Mineralocorticoid receptor as a therapeutic target in chronic kidney disease and hypertension
Published Date
Oct 20, 2016
Journal
Volume
40
Issue
3
Pages
221 - 225
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