Relative effect of APOE ε4 on neuroimaging biomarker changes across the lifespan

Volume: 87, Issue: 16, Pages: 1696 - 1703
Published: Oct 18, 2016
Abstract
To provide a comprehensive understanding of APOE ε4 effects across the lifespan on the 3 main neuroimaging biomarkers.Two hundred seven community-dwelling, cognitively normal APOE ε4 carriers and noncarriers aged 20-87 years were involved in this study. They underwent structural MRI, fluorodeoxyglucose-PET, and florbetapir-PET scans. The effects of APOE, age, and APOE × age interaction were assessed voxel-wise for each modality.There was no...
Paper Details
Title
Relative effect of APOE ε4 on neuroimaging biomarker changes across the lifespan
Published Date
Oct 18, 2016
Journal
Volume
87
Issue
16
Pages
1696 - 1703
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