Hyaluronic acid fillers with cohesive polydensified matrix for soft-tissue augmentation and rejuvenation: a literature review

Background: Cohesive monophasic polydensified fillers show unique viscoelastic properties and variable density of hyaluronic acid, allowing for a homogeneous tissue integration and distribution of the material. Objective: The aim of this paper was to review the clinical data regarding the performance, tolerability, and safety of the Belotero ® fillers for soft-tissue augmentation and rejuvenation. Methods: A literature search was performed up...