Interictal epileptic discharge correlates with global and frontal cognitive dysfunction in temporal lobe epilepsy

Temporal lobe epilepsy (TLE) with hippocampal sclerosis has widespread effects on structural and functional connectivity and often entails cognitive dysfunction. EEG is mandatory to disentangle interactions in epileptic and physiological networks which underlie these cognitive comorbidities. Here, we examined how interictal epileptic discharges (IEDs) affect cognitive performance.Thirty-four patients (right TLE=17, left TLE=17) were examined...