Change in Bone Mineral Density Is an Indicator of Treatment-Related Antifracture Effect in Routine Clinical Practice

Whether change in bone mineral density (BMD) is an accurate indicator of antifracture effect in clinical practice is unknown.To evaluate repeated BMD testing as an indicator of treatment-related fracture risk reduction.Registry-based cohort study.Manitoba, Canada.6629 women aged 40 years or older initiating osteoporosis treatment with 2 consecutive dual-energy x-ray absorptiometry scans (mean interval, 4.5 years).Change in BMD between the first...