Associations between anti-Ro52 antibodies and lung fibrosis in mixed connective tissue disease

Objective. MCTD is a chronic, immune-mediated disorder defined by the combined presence of serum anti-RNP antibodies and distinct clinical features, including progressive lung fibrosis. The aim of the study was to evaluate the potential impact of anti-SSA (i.e. Ro52 and Ro60) and anti-SSB autoantibodies as markers for disease outcomes in MCTD. Methods. Stored serum samples from 113 patients included in the cross-sectional, nationwide Norwegian...