First application of a pixel-wise analysis on bladder dose–surface maps in prostate cancer radiotherapy

Purpose To develop a method for investigating local dose effects on the bladder after prostate cancer radiotherapy based on dose–surface maps (DSMs). Background and purpose DSMs of patients included in a prospective study (DUE01) were generated by virtually cutting bladder contours at the points intersecting the sagittal plane passing through its center-of-mass: maps were laterally normalized and aligned at the posterior inferior point. The...