Radiotherapy and Oncology
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#1R.L. Hachadorian (Dartmouth College)H-Index: 2
Last. Lesley A. Jarvis (Dartmouth–Hitchcock Medical Center)H-Index: 15
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PURPOSE In mono-isocentric radiation therapy treatment plans designed to treat the whole breastand supraclavicular lymph nodes, the fields meet at isocenter, forming the match line. Insufficient coverage at the match line can lead to recurrence and overlap over weeks of treatment can lead to increased risk of healthy tissue toxicity. Cherenkov imaging was used to assess the accuracy of delivery at the match line and identify potential incidents during patient treatments. METHODS AND MATERIALS A ...
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#1Stephen F Kry (University of Texas MD Anderson Cancer Center)H-Index: 36
#2Jessica Lye (Australian Radiation Protection and Nuclear Safety Agency)H-Index: 12
Last. Joerg LehmannH-Index: 19
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Abstract Purpose To promote consistency in clinical trials by recommending a uniform framework as it relates to radiation transport and dose calculation in water versus in medium. Methods The Global Quality Assurance of Radiation Therapy Clinical Trials Harmonisation Group (GHG; www.rtqaharmonization.org ) compared the differences between dose to water in water (Dw,w), dose to water in medium (Dw,m), and dose to medium in medium (Dm,m). This was done based on a review of historical frameworks, e...
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#1Elaine Cha (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 1
#2Sharif Elguindi (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 3
Last. Erin F. Gillespie (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 8
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Abstract Background and Purpose Artificial intelligence advances have stimulated a new generation of autosegmentation, however clinical evaluations of these algorithms are lacking. This study assesses the clinical utility of deep learning-based autosegmentation for MR-based prostate radiotherapy planning. Materials and Methods Data was collected prospectively for patients undergoing prostate-only radiation at our institution from June to December 2019. Geometric indices (volumetric Dice-Sorensen...
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#1Michael Dubec (University of Manchester)H-Index: 5
#2Stephanie Brown (Cheltenham General Hospital)H-Index: 2
Last. David Cobben (University of Manchester)H-Index: 13
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Abstract Purpose This study compared MRI to CBCT for the identification and registration of lymph nodes (LN) in patients with locally advanced (LA)-NSCLC, to assess the suitability of targeting LNs in future MR-image guided radiotherapy (MRgRT) workflows. Method Radiotherapy radiographers carried out Visual Grading Analysis (VGA) assessment of image quality, LN registration and graded their confidence in registration for each of the 24 LNs on CBCT and two MR sequences, MR1 (T2w Turbo Spin Echo) ...
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#1Ying Zhang (SJTU: Shanghai Jiao Tong University)
#2Wen Feng (SJTU: Shanghai Jiao Tong University)H-Index: 5
Last. Wen Yu (SJTU: Shanghai Jiao Tong University)H-Index: 6
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BACKGROUND To observe the long-term survival and late adverse events in a phase Ⅰ/Ⅱ trial (NCT01843049) of dose escalation for thoracic esophageal squamous cell carcinoma (ESCC) with simultaneous integrated boost (SIB) technique. METHODS Patients with ESCC were treated with escalating radiation dose of four predefined levels. Dose of 62.5-64Gy/25-32 fractions was delivered to the gross tumor volume (GTV), with (Level 3&4) or without (Level 1&2) a SIB up to 70 Gy for pre-treatment 50% SUVmax area...
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#1Lena Nenoff (Paul Scherrer Institute)H-Index: 4
#2Michael Matter (Paul Scherrer Institute)H-Index: 4
Last. Francesca Albertini (Paul Scherrer Institute)H-Index: 19
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PURPOSE A major burden of introducing an online daily adaptive proton therapy (DAPT) workflow is the time and resources needed to correct the daily propagated contours. In this study, we evaluated the dosimetric impact of neglecting the online correction of the propagated contours in a DAPT workflow. MATERIAL AND METHODS For five NSCLC patients with nine repeated deep-inspiration breath-hold CTs, proton therapy plans were optimised on the planning CT to deliver 60Gy-RBE in 30 fractions. All repe...
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#1Esmée A Dijkstra (UG: University of Groningen)H-Index: 3
#2Veronique E.M. Mul (UG: University of Groningen)H-Index: 15
Last. Boudewijn van Etten (UG: University of Groningen)H-Index: 11
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BACKGROUND AND PURPOSE A radical resection of locally advanced rectal cancer (LARC) or recurrent rectal cancer (RRC) can be challenging. In case of increased risk of an R1 resection, intra-operative brachytherapy (IOBT) can be applied. We evaluated the clinical selection strategy for IOBT. MATERIALS AND METHODS Between February 2007 and May 2018, 132 LARC/RRC patients who were scheduled for surgery with IOBT standby, were evaluated. By intra-operative inspection of the resection margin and MR im...
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#1Yoko Tsukita (Tohoku University)H-Index: 5
#2Takaya Yamamoto (Tohoku University)H-Index: 12
Last. Hisatoshi Sugiura (Tohoku University)H-Index: 31
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Abstract Background and purpose Intensity-modulated radiation therapy (IMRT) is increasingly applied in concurrent chemoradiotherapy (CCRT) for locally-advanced non-small cell lung cancer (NSCLC), with improvement of target coverage and better sparing of normal tissue. IMRT tends to have a larger low-dose irradiation volume than 3D conformal radiotherapy, but the incidence of and risk factors for pneumonitis remain unclear, especially following the approval of durvalumab. Materials and Methods W...
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#1Umesh MahantshettyH-Index: 25
#2Richard Poetter (Medical University of Vienna)H-Index: 11
Last. N. Amornwichet (Chula: Chulalongkorn University)H-Index: 6
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Abstract MR Imaging is regarded as the gold standard for Image Gudied Adaptive Brachytherapy (IGABT) for cervical cancer. However, its wide applicability is limited by its availability, logistics and financial implications. Use of alternative imaging like CTand Ultrasound (US) for IGABT has been attempted. In order to arrive at a systematic, uniform and international approach for CT based definition and contouring of target structures, GEC ESTRO, IBS and ABS agreed to jointly develop such recomm...
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#1Daniëlle B.P. Eekers (Maastricht University Medical Centre)H-Index: 15
#2Dario Di Perri (Cliniques Universitaires Saint-Luc)H-Index: 5
Last. Esther G.C. TroostH-Index: 34
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Abstract Background and purpose To update the digital online atlas for organs at risk (OARs) delineation in neuro-oncology based on high-quality computed tomography (CT) and magnetic resonance (MR) imaging with new OARs. Materials and methods In this planned update of the neurological contouring atlas published in 2018, ten new clinically relevant OARs were included, after thorough discussion between experienced neuro-radiation oncologists (RTOs) representing 30 European radiotherapy-oncology in...
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