Original paper
Integrin-linked kinase activity modulates the pro-metastatic behavior of ovarian cancer cells
Abstract
Epithelial ovarian cancer (EOC) is the most fatal gynecologic cancer in the U.S., resulting in >14,000 deaths/year. Most women are diagnosed at late stage with widely disseminated intra-peritoneal metastatic disease, resulting in a 5-year survival rate of <30%. EOCs spread via direct extension and exfoliation into the peritoneal cavity, adhesion to peritoneal mesothelial cells, mesothelial cell retraction to expose sub-mseothelial matrix and...
Paper Details
Title
Integrin-linked kinase activity modulates the pro-metastatic behavior of ovarian cancer cells
Published Date
Mar 3, 2016
Journal
Volume
7
Issue
16
Pages
21968 - 21981
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Notes
History