Oncotarget
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#1Anne E O'SheaH-Index: 3
#2Guy T. CliftonH-Index: 17
Last. George E. PeoplesH-Index: 24
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#1Manabu Seino (YU : Yamagata University)H-Index: 11
#2Tsuyoshi Ohta (YU : Yamagata University)H-Index: 18
Last. Nobuo Yaegashi (Tohoku University)H-Index: 67
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#1Yihe YanH-Index: 6
#2Leting ZhengH-Index: 2
Last. David A. GellerH-Index: 90
view all 4 authors...
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#1Timothy Craig Allen (UMMC: University of Mississippi Medical Center)H-Index: 6
#2Yan Xiao (Roche)H-Index: 1
Last. Eric H. Bernicker (Houston Methodist)H-Index: 13
view all 10 authors...
Objective null This study assessed the prevalence of anaplastic lymphoma kinase (ALK) rearrangements in US oncology practices. null Materials and methods null Using a nationwide real-world database, we included adults with advanced non-small cell lung cancer (aNSCLC, stage IIIB- IV) diagnosed January 2015 - May 2019, with documented ALK testing results and smoking status. Rearrangement prevalence was assessed overall and then stratified by patient characteristics. null Results null The cohort in...
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#1Phyllis A. Gimotty (University of Pennsylvania)H-Index: 67
#2Jacob Till (University of Pennsylvania)H-Index: 10
Last. Bryson W. Katona (University of Pennsylvania)H-Index: 16
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Patients newly diagnosed with metastatic pancreatic ductal adenocarcinoma generally have poor survival, with heterogeneous rates of progression. Biomarkers that could predict progression and/or survival would help inform patients and providers as they make care decisions. In a previous retrospective study, we discovered that circulating thrombospondin-2 (THBS2) could, in combination with CA19-9, better distinguish patients with PDAC versus healthy controls. Here we evaluated whether THBS2 levels...
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#1John W. RutlandH-Index: 7
Last. Raj K. ShrivastavaH-Index: 15
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MET gene alterations are known to be involved in acquired resistance to epidermal growth factor receptor inhibition. MET amplifications present a potential therapeutic target in non-small cell lung cancer. Although next-generation sequencing (NGS) and fluorescence in situ hybridization (FISH) are conventionally used to assess MET amplifications, there are currently no clinically defined cut-off values for NGS, with FISH still being the gold standard. A collective of 20 formalin-fixed paraffin-em...
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#1Sasagu KurozumiH-Index: 13
#2Ayaka KatayamaH-Index: 8
Last. Emad A. RakhaH-Index: 73
view all 5 authors...
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#1Ana Chor (UFRJ: Federal University of Rio de Janeiro)H-Index: 1
#2Maria Adriana Skeff (UFRJ: Federal University of Rio de Janeiro)H-Index: 1
Last. Valeria de Mello Coelho (UFRJ: Federal University of Rio de Janeiro)H-Index: 3
view all 8 authors...
Clinical guidelines for oral mucositis (OM) still consist in palliative care. Herein, we summarize cellular and molecular mechanisms of OM ulceration in response to chemical therapies in animal models. We discuss evidenced anti-inflammatory and anti-oxidant drugs which have not been ever used for OM, such as synthetic peptides as well as cell therapy with mesenchymal stem cells; amniotic membranes, mucoadhesive polymers loaded with anti-inflammatory agents and natural or synthetic electrospun. T...
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