Papers 10000
1 page of 1,000 pages (10k results)
#1Alexander BridgesH-Index: 1
#2Ranjit K. MehtaH-Index: 3
Last. Mukesh K. NyatiH-Index: 26
view all 6 authors...
#1Mujib UllahH-Index: 14
Last. Gustavo YannarelliH-Index: 17
view all 3 authors...
#1Robert Harrison Hester (University of Texas MD Anderson Cancer Center)H-Index: 1
#2Shailesh M AdvaniH-Index: 19
Last. Cathy Eng (Vandy: Vanderbilt University)H-Index: 66
view all 19 authors...
BACKGROUND The clinical utility of a blood-based biomarker in squamous cell carcinoma of the anus (SCCA) is unknown. We analyzed carcinoembryonic antigen (CEA), a commonly employed assay for patients with colorectal adenocarcinoma, as a serum biomarker for patients with biopsy-proven SCCA. MATERIALS AND METHODS Medical records from 219 patients with biopsy-proven SCCA at the University of Texas MD Anderson Cancer Center were reviewed under an IRB-approved protocol from 2013 to 2020 to assess for...
#1Rami MäkeläH-Index: 1
#2Ville Härmä (University of Sheffield)H-Index: 7
Last. Juha Rantala (University of Sheffield)H-Index: 18
view all 8 authors...
Cutaneous apocrine carcinoma is an extreme rare malignancy derived from a sweat gland. Histologically sweat gland cancers resemble metastatic mammary apocrine carcinomas, but the genetic landscape remains poorly understood. Here, we report a rare metastatic case with a PALB2 aberration identified previously as a familial susceptibility gene for breast cancer in the Finnish population. As PALB2 exhibits functions in the BRCA1/2-RAD51-dependent homologous DNA recombination repair pathway, we sough...
#1Shweta Kishor Sonawane (AcSIR: Academy of Scientific and Innovative Research)H-Index: 4
#2Subashchandrabose Chinnathambi (AcSIR: Academy of Scientific and Innovative Research)H-Index: 16
BACKGROUND Alzheimer's disease is a type of dementia denoted by progressive neuronal death due to the accumulation of proteinaceous aggregates of Tau. Post-translational modifications like hyperphosphorylation, truncation, glycation, etc. play a pivotal role in Tau pathogenesis. Glycation of Tau aids in paired helical filament formation and abates its microtubule-binding function. The chemical modulators of Tau PTMs, such as kinase inhibitors and antibody-based therapeutics, have been developed,...
#1Chiara Colarusso (UNISA: University of Salerno)H-Index: 9
#2Michela Terlizzi (UNISA: University of Salerno)H-Index: 12
Last. Rosalinda Sorrentino (UNISA: University of Salerno)H-Index: 25
view all 8 authors...
Cigarette smoking is the leading risk factor for COPD and lung cancer establishment. Epidemiologically, COPD patients are 6.35 times more likely to develop lung cancer. To mimic COPD, we exposed mice to nose-only cigarette smoke and used human samples of lung adenocarcinoma patients according to the smoking and COPD status. Smoking C57Bl/6N mice had higher enlargement of alveoli, deposition of collagen and mucus production, associated to the release of IL-1-like cytokines, such as IL-1α and IL-1...
#1Marco Rubatto (UNITO: University of Turin)H-Index: 2
#2Martina Merli (UNITO: University of Turin)
Last. Pietro Quaglino (UNITO: University of Turin)H-Index: 51
view all 12 authors...
Xeroderma Pigmentosum (XP) is a rare genetic disorder with a poor prognosis due to high photosensitivity in affected patients. Herein, we describe the first case of the use of cemiplimab in a patient with XP, a 19-year-old girl presented with locally advanced squamous cell carcinoma of the right periorbital and nasal region. This treatment has been undertaken after a cycle of proton beam radiotherapy. Besides, it is reported a description of the few cases in the literature describing the effecti...
#1Samantha EpistolioH-Index: 3
Last. Piercarlo SalettiH-Index: 29
view all 10 authors...
BACKGROUND A disappearance of RAS mutations in the plasma of about 50% of mCRCs (metastatic colorectal cancers) treated with bevacizumab-based chemotherapy has been reported. Our aim was to evaluate the same issue at tissue level. MATERIALS AND METHODS Using next-generation sequencing and real-time PCR approaches, we characterized the primary tumor (PT) and paired liver metastases in 28 RAS mutant mCRCs. Patients were subdivided into 3 treatment groups: 1) bevacizumab plus chemotherapy; 2) chemo...
#1Esther Baruch (BIU: Bar-Ilan University)
#2Tali Nizri-Megnaji (BIU: Bar-Ilan University)H-Index: 1
Last. Doron Ginsberg (BIU: Bar-Ilan University)H-Index: 33
view all 4 authors...
The transcription factor E2F1 induces both proliferation and apoptosis and is a critical downstream target of the tumor suppressor RB. Long non-coding RNAs (lncRNAs) are major regulators of many cellular processes, including cell cycle progression and cell proliferation. However, the mode of action as well as the transcriptional regulation of most lncRNAs are only beginning to be understood. Here, we report that a novel human lncRNA, LAPAS1, is an E2F1- regulated lncRNA that affects S phase prog...
Top fields of study
Cancer research