Original paper
Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease
Abstract
Recent evidence from cross-sectional in vivo imaging studies suggests that atrophy of the cholinergic basal forebrain (BF) in Alzheimer's disease (AD) can be distinguished from normal age-related degeneration even at predementia stages of the disease. Longitudinal study designs are needed to specify the dynamics of BF degeneration in the transition from normal aging to AD. We applied recently developed techniques for in vivo volumetry of the BF...
Paper Details
Title
Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease
Published Date
Apr 1, 2013
Journal
Volume
34
Issue
4
Pages
1210 - 1220
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Notes
History