Original paper
Striatal dysfunction during reversal learning in unmedicated schizophrenia patients
Abstract
Subjects with schizophrenia are impaired at reinforcement-driven reversal learning from as early as their first episode. The neurobiological basis of this deficit is unknown. We obtained behavioral and fMRI data in 24 unmedicated, primarily first episode, schizophrenia patients and 24 age-, IQ- and gender-matched healthy controls during a reversal learning task. We supplemented our fMRI analysis, focusing on learning from prediction errors, with...
Paper Details
Title
Striatal dysfunction during reversal learning in unmedicated schizophrenia patients
Published Date
Apr 1, 2014
Journal
Volume
89
Pages
171 - 180
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