¹⁸F-FLT PET During Radiotherapy or Chemoradiotherapy in Head and Neck Squamous Cell Carcinoma Is an Early Predictor of Outcome

This prospective study used sequential PET with the proliferation tracer 3′-deoxy-3′-¹⁸F-fluorothymidine (¹⁸F-FLT) to monitor the early response to treatment of head and neck cancer and evaluated the association between PET parameters and clinical outcome. Methods: Forty-eight patients with head and neck cancer underwent ¹⁸F-FLT PET/CT before and during the second and fourth weeks of radiotherapy or...