Natural History of Early, Localized Prostate Cancer: A Final Report from Three Decades of Follow-up

Most localized prostate cancers are believed to have an indolent course. Within 15 yr of diagnosis, most deaths among men with prostate cancer (PCa) can be attributed to other competing causes. However, data from studies with extended follow-up are insufficient to determine appropriate treatment for men with localized disease.To investigate the long-term natural history of untreated, early-stage PCa.We conducted a population-based,...