Rapid Detection of SNP (c.309T>G) in the MDM2 Gene by the Duplex SmartAmp Method
Abstract
Background Genetic polymorphisms in the human MDM2 gene are suggested to be a tumor susceptibility marker and a prognostic factor for cancer. It has been reported that a single nucleotide polymorphism (SNP) c.309T>G in the MDM2 gene attenuates the tumor suppressor activity of p53 and accelerates tumor formation in humans. Methodology In this study, to detect the SNP c.309T>G in the MDM2 gene, we have developed a new SNP detection method, named...
Paper Details
Title
Rapid Detection of SNP (c.309T>G) in the MDM2 Gene by the Duplex SmartAmp Method
Published Date
Apr 2, 2013
Journal
Volume
8
Issue
4
Pages
e60151 - e60151
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