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#1Fabienne Mazerolles (INSERM: Inserm)H-Index: 17
#2Frédéric Rieux-Laucat (INSERM: Inserm)H-Index: 56
The T cell expression of various co-signalling receptors from the CD28 immunoglobulin superfamily (Inducible T cell co-stimulator (ICOS), Programmed cell death 1(PD-1), cytotoxic T lymphocyte associated protein 4 (CTLA-4), B and T lymphocyte attenuator (BTLA) or from the tumour necrosis factor receptor superfamily (glucocorticoid-induced TNFR family related (GITR), 4-1BB, and CD27), is essential for T cell responses regulation. Other receptors (such as T cell immunoglobulin and mucin domain-cont...
#1Azmeraw Ambachew Kebede (University of Gondar)H-Index: 2
#2Birhan Tsegaw Taye (DBU: Debre Berhan University)H-Index: 1
Last. Muhabaw Shumye Mihret (University of Gondar)H-Index: 4
view all 6 authors...
Background Coronavirus disease 19 (COVID-19) is a newly emerging pandemic affecting more than 120 million people globally. Compliance with preventive practices is the single most effective method to overcome the disease. Although several studies have been conducted regarding COVID-19, data on healthcare provider’s adherence to COVID-19 preventive practices during childbirth through direct observation is limited. Therefore, this study aimed to assess healthcare provider’s adherence to COVID-19 pr...
#1Nadine A. Vogt (Ontario Veterinary College)H-Index: 3
#2Benjamin M. Hetman (Ontario Veterinary College)H-Index: 1
Last. Nicole Ricker (Ontario Veterinary College)H-Index: 8
view all 13 authors...
To better understand the contribution of wildlife to the dissemination of Salmonella and antimicrobial resistance in Salmonella and Escherichia coli, we examined whole-genome sequence data from Salmonella and E. coli isolates collected from raccoons (Procyon lotor) and environmental sources on farms in southern Ontario. All Salmonella and phenotypically resistant E. coli collected from raccoons, soil, and manure pits on five swine farms as part of a previous study were included. We assessed for ...
#1Chikako Nakama (KMU: Kansai Medical University)
#2Takahiro TabuchiH-Index: 25
Heated tobacco products (HTPs) have become popular recently. People with chronic disease, such as diabetes, cardiovascular disease (CVD), chronic obstructive pulmonary disease (COPD) and cancer, should quit smoking for treatment and recurrence of tobacco-related diseases. However, they have difficulty in quitting smoking, and they may start HTPs use to quit smoking. The purpose of this study is to examine the use of HTPs in people with chronic disease. We used data from an internet study, the Ja...
#1Thomas B. P. Oldenburg (UoC: University of Calgary)H-Index: 18
#2Melisa Brown (UoC: University of Calgary)H-Index: 4
Last. Julio MercaderH-Index: 21
view all 7 authors...
This work introduces a novel analytical chemistry method potentially applicable to the study of archaeological starch residues. The investigation involved the laboratory synthesis of model Maillard reaction mixtures and their analysis through Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry (FTICR-MS). Thus, starch from sixteen plant species were matured while reacting it with the amino acid glycine. The FTICR-MS analysis revealed > 5,300 molecular compounds, with numerous unique hete...
#1Amit Mahindra (University of Glasgow)H-Index: 5
#2Gonzalo S Tejeda (University of Glasgow)H-Index: 10
Last. Brian D. Hudson (University of Glasgow)H-Index: 32
view all 16 authors...
SARS-CoV-2 viral attachment and entry into host cells is mediated by a direct interaction between viral spike glycoproteins and membrane bound angiotensin-converting enzyme 2 (ACE2). The receptor binding motif (RBM), located within the S1 subunit of the spike protein, incorporates the majority of known ACE2 contact residues responsible for high affinity binding and associated virulence. Observation of existing crystal structures of the SARS-CoV-2 receptor binding domain (SRBD)-ACE2 interface, co...
#1Stacy M Endres-Dighe (RTP: Research Triangle Park Foundation)H-Index: 6
#2Kasey Jones (RTP: Research Triangle Park Foundation)H-Index: 4
Last. Sarah Rhea (RTP: Research Triangle Park Foundation)H-Index: 7
view all 8 authors...
The first case of COVID-19 was detected in North Carolina (NC) on March 3, 2020. By the end of April, the number of confirmed cases had soared to over 10,000. NC health systems faced intense strain to support surging intensive care unit admissions and avert hospital capacity and resource saturation. Forecasting techniques can be used to provide public health decision makers with reliable data needed to better prepare for and respond to public health crises. Hospitalization forecasts in particula...
#1Ulrike Baum (THL: Finnish Institute for Health and Welfare)H-Index: 3
#2Poukka Ej (THL: Finnish Institute for Health and Welfare)H-Index: 2
Last. Tuija Leino (THL: Finnish Institute for Health and Welfare)H-Index: 12
view all 6 authors...
BackgroundIn Finland, both mRNA and adenovirus vector (AdV) Covid-19 vaccines have been used after the vaccination campaign started on December 27, 2020. Vaccination of the elderly and chronically ill was prioritized and the interval between doses set to 12 weeks. The objective of this interim analysis was to evaluate first and second dose vaccine effectiveness (VE) in a real-world setting. MethodsDuring the first 5 months of the campaign, a register-based cohort study was conducted in the Finni...
#1Bilal Ahmed Usmani (NED University of Engineering and Technology)H-Index: 2
#2Mustafain Ali (NED University of Engineering and Technology)
Last. Saad Ahmed Qazi (NED University of Engineering and Technology)H-Index: 6
view all 7 authors...
The province of Sindh reported the first COVID-19 case in Pakistan on 26th February 2020. The Government of Sindh has employed numerous control measures to limit its spread. However, for low-and middle-income countries such as Pakistan, the management protocols for controlling a pandemic are not always as definitive as they would be in other developed nations. Given the dire socio-economic conditions of Sindh, continuation of province-wise lockdowns may inadvertently cause a potential economic b...
#1Helen BadgeH-Index: 4
#2Tim Churches (UNSW: UNSW Sydney)H-Index: 21
Last. Ian A. HarrisH-Index: 53
view all 10 authors...
Background Total hip and total knee replacement (THR/TKR) are common and effective surgeries to reduce the pain and disability associated with arthritis but are associated with small but significant risks of preventable complications such as surgical site infection (SSI) and venous-thrombo-embolism (VTE). This study aims to determine the degree to which hospital care was compliant with clinical guidelines for the prevention of SSI and VTE after THR/TKR; and whether non-compliant prophylaxis is a...
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