Original paper
Chronic alcohol ingestion induces osteoclastogenesis and bone loss through IL-6 in mice
Abstract
To investigate the role of IL-6 in alcohol-mediated osteoporosis, we measured a variety of bone remodeling parameters in wild-type (il6(+/+)) or IL-6 gene knockout (il6(-/-)) mice that were fed either control or ethanol liquid diets for 4 months. In the il6(+/+) mice, ethanol ingestion decreased bone mineral density, as determined by dual-energy densitometry; decreased cancellous bone volume and trabecular width and increased trabecular spacing...
Paper Details
Title
Chronic alcohol ingestion induces osteoclastogenesis and bone loss through IL-6 in mice
Published Date
Oct 1, 2000
Volume
106
Issue
7
Pages
887 - 895
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Notes
History