Imaging of Inflammation by PET, Conventional Scintigraphy, and Other Imaging Techniques

Published on Sep 1, 2013in The Journal of Nuclear Medicine7.887
· DOI :10.2967/JNUMED.110.076232
Martin Gotthardt14
Estimated H-index: 14
(Radboud University Nijmegen Medical Centre),
Chantal P. Bleeker-Rovers36
Estimated H-index: 36
(Radboud University Nijmegen Medical Centre)
+ 1 AuthorsWim J.G. Oyen84
Estimated H-index: 84
(Radboud University Nijmegen Medical Centre)
Nuclear medicine imaging procedures play an important role in the assessment of inflammatory diseases. With the advent of 3-dimensional anatomic imaging, there has been a tendency to replace traditional planar scintigraphy by CT or MRI. Furthermore, scintigraphic techniques may have to be combined with other imaging modalities to achieve high sensitivity and specificity, and some may require time-consuming labeling procedures. On the other hand, new developments such as combined SPECT/CT increase the diagnostic power of scintigraphy. Also, the advent of PET had a considerable impact on the use of nuclear medicine imaging techniques. In this review, we aim to provide nuclear medicine specialists and clinicians with the relevant information on rational and efficient use of nuclear medicine imaging techniques in the assessment of patients with osteomyelitis, infected vascular prostheses, metastatic infectious disease, rheumatoid arthritis, vasculitis, inflammatory bowel disease, sarcoidosis, and fever of unknown origin.
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