Fibrosing mediastinitis manifesting as thoracic prevertebral thin band-like mass on MRI and PET-CT.

Published on Jul 1, 2007in British Journal of Radiology2.196
· DOI :10.1259/BJR/98272327
Kyung-Yung Lee9
Estimated H-index: 9
(Konkuk University),
J G Yi1
Estimated H-index: 1
+ 3 AuthorsJin Sung Kim15
Estimated H-index: 15
To our knowledge, no report exists of a posterior mediastinal thin band-like mass as a manifestation of fibrosing mediastinitis. A man showed right pleural effusion on chest radiograph. On CT, there was a band-like mass on thoracic prevertebral area. MRI demonstrated the enhancing longitudinal band-like mass all along the vertebrae on coronal and sagittal scans. It was hypermetabolic on PET–CT and there was another hot mass in the presacral area. Additional pelvic MRI showed presacral mass with aortic encasement. Biopsy specimen was consistent with fibrosing mediastinitis. We report a case of fibrosing mediastinitis of posterior mediastinum manifesting as thoracic prevertebral band-like mass and discontiguous presacral, periaortic mass studied with CT, MRI and PET-CT.
📖 Papers frequently viewed together
16 Citations
6 Citations
#1Byung Kwan Park (Seoul National University Hospital)H-Index: 2
#2Soonhag KimH-Index: 28
Last. M H MoonH-Index: 1
view all 3 authors...
Retroperitoneal fibrosis is characteristic plaques of dense fibrous tissue, typically extending from the level of the kidney down to the sacral promontory. Involvement of the presacral space is extremely rare in retroperitoneal fibrosis. We report two cases of idiopathic retroperitoneal fibrosis manifested by a presacral mass.
7 CitationsSource
#1Muhammad Imran (Tohoku University)H-Index: 74
#2Kazuo KubotaH-Index: 43
Last. Masatoshi ItohH-Index: 45
view all 10 authors...
Whole-body serial positron emission tomography scanning was done using fluorine-18 fluorodeoxygluclose (F-18 FDG) in a patient with a mediastinal mass. Uptake correlated well with the clinical symptoms and aggressiveness of the disease. Based on the F-18 FDG findings, a biopsy specimen was taken from the active region of the mass, which confirmed the diagnosis of sclerosing mediastinitis.
24 CitationsSource
#1J. Y. LeeH-Index: 1
#2Y. KimH-Index: 1
Last. Man Pyo ChungH-Index: 1
view all 4 authors...
20 CitationsSource
#1T M MoleH-Index: 1
#2J GloverH-Index: 1
Last. M N SheppardH-Index: 1
view all 3 authors...
BACKGROUND--Sclerosing mediastinitis is a rare condition which causes dense fibrosis of the mediastinum. Few large studies have been reported to date. The clinical and pathological features of cases have been studied in a specialist referral centre in the UK. METHODS--The pathological files of the Royal Brompton Hospital were examined and 18 cases of sclerosing mediastinitis were identified between 1970 and 1993. The clinical notes were obtained and the pathological specimens analysed. RESULTS--...
73 CitationsSource
#1Andrew D. Sherrick (UR: University of Rochester)H-Index: 1
#2Larry R. Brown (UR: University of Rochester)H-Index: 1
Last. Jeffrey L. Myers (UR: University of Rochester)H-Index: 5
view all 4 authors...
We retrospectively reviewed the radiographic findings of fibrosing mediastinitis (FM) in 33 patients. Imaging studies included chest radiographs, computed tomographic scans, magnetic resonance imaging examinations, esophograms, ventilation perfusion scans, angiograms, and venograms. Findings include bronchial narrowing in 11 patients (33 percent), pulmonary artery obstruction/narrowing in 6 patients (18 percent), esophageal narrowing in 3 patients (9 percent), and superior vena cava obstruction/...
119 CitationsSource
#1Douglas J. Mathisen (Harvard University)H-Index: 71
#2Hermes C. Grillo (Harvard University)H-Index: 69
Abstract We treated 20 patients thought to have mediastinal fibrosis secondary to Histoplasma capsulatum . All but 1 were symptomatic. The most common symptoms were dyspnea (8), hemoptysis (6), postobstructive pneumonia (5), and superior vena caval obstruction (2). Nine patients had severe stenosis of the trachea, carina, or main bronchus. Special stains identified Histoplasma capsulatum in surgical specimens in 9 patients. Surgical procedures were done for 18 of 20 patients (resection of subcar...
68 CitationsSource
#1PD Kountz (WashU: Washington University in St. Louis)H-Index: 1
#2P. L. Molina (WashU: Washington University in St. Louis)H-Index: 16
Last. Stuart S. Sagel (WashU: Washington University in St. Louis)H-Index: 43
view all 3 authors...
Ce serait une reponse auto-immune hypersensible a des antigenes divers. Un cas d'homme de 63 ans presentant une masse mediastinale posterieure
7 CitationsSource
Cited By8
#1Hee Kang (Kosin University Gospel Hospital)
#2Min Jung Jung (Kosin University Gospel Hospital)
Abstract Fibrosing mediastinitis is an uncommon benign disorder in which a chronic inflammatory reaction results in diffuse fibrosis of the mediastinum, potentially compromising the airways, great vessels and other mediastinal structures. Herein we describe a progressive course of fibrosing mediastinitis in a 72-year-old man. Computed tomography images depicted a diffuse, infiltrative, soft tissue mass involving the esophagus and superior vena cava in the mediastinum. Magnetic resonance imaging ...
Mediastinal fibrosis is a rare disease characterised by fibrous proliferation in the mediastinum. It can be idiopathic or secondary to several conditions such as infections and malignancies. Anecdotal reports have described idiopathic mediastinal fibrosis (IMF) in association with other fibro-inflammatory or autoimmune diseases. We report nine new IMF cases recently seen at our Fibro-Inflammatory Disease Clinic and reviewed the IMF cases reported in the English language literature throughout 200...
13 CitationsSource
#1Michael F. McNeeley (UW: University of Washington)H-Index: 9
#2Jonathan H. Chung (University of Colorado Denver)H-Index: 28
Last. J. David Godwin (UW: University of Washington)H-Index: 19
view all 4 authors...
OBJECTIVE. The purpose of this article is to review and illustrate the pathogenesis, natural history, imaging features, and treatment of granulomatous fibrosing mediastinitis. CONCLUSION. Granulomatous fibrosing mediastinitis is an infiltrative disorder characterized by encasement of the mediastinal viscera; in most cases in the United States, it represents an idiosyncratic immune response to histoplasma. Familiarity with the various imaging features of fibrosing mediastinitis is important for p...
32 CitationsSource
#1Tobias Peikert (Mayo Clinic)H-Index: 29
#2Thomas V. ColbyH-Index: 105
Last. Ulrich SpecksH-Index: 63
view all 7 authors...
Fibrosing mediastinitis (FM) is a rare disorder characterized by the invasive proliferation of fibrous tissue within the mediastinum. FM frequently results in the compression of vital mediastinal structures and has been associated with substantial morbidity and mortality. Its pathogenesis remains unknown. However, in North America most cases are thought to represent an immune-mediated hypersensitivity response to Histoplasma capsulatum infection. To characterize the clinical disease spectrum, na...
71 CitationsSource
#1Takuya OnukiH-Index: 9
#2Shigemi Ishikawa (International University of Health and Welfare)H-Index: 1
Last. Masaharu InagakiH-Index: 9
view all 5 authors...
Sclerosing mediastinitis is a rare, benign disorder that is often indistinguishable from malignancy by conventional imaging techniques. The value of fluorodeoxyglucose positron emission tomography (FDG-PET) imaging in the diagnosis of this disorder has not been elucidated. Recently, a few studies have reported the use of dual-phase FDG-PET imaging in the diagnosis of malignancies. The dual phase contains early- and late- phase images. The maximum standard uptake value (SUVmax) of late phase imag...
2 CitationsSource
#1Paulo Barreto (Paris V: Paris Descartes University)H-Index: 1
#2Christian Pagnoux (Paris V: Paris Descartes University)H-Index: 35
Last. Loïc Guillevin (Paris V: Paris Descartes University)H-Index: 98
view all 8 authors...
Abstract Retroperitoneal fibrosis has been reported in several patients with Wegener granulomatosis (WG), but only three isolated cases of dorsal prevertebral lesions, closely resembling fibrosing mediastinitis, have been published so far. We describe four new WG patients (two men, two women), 49–59 years old at diagnosis, with dorsal prevertebral lesions, mainly right-sided, and with adjacent pleural thickening in two. These lesions were detected on computed-tomography scans at diagnosis in two...
16 CitationsSource
#1Paulo Barreto (Paris V: Paris Descartes University)H-Index: 1
#2Christian Pagnoux (Paris V: Paris Descartes University)H-Index: 35
Last. Loïc Guillevin (Paris V: Paris Descartes University)H-Index: 98
view all 8 authors...
Resume La survenue d’une fibrose retroperitoneale a ete rapportee chez plusieurs patients atteints de granulomatose de Wegener (GW), mais seuls trois cas isoles de lesions dorsales prevertebrales, ressemblant fortement a une mediastinite fibrosante, ont ete publies a ce jour. Nous rapportons quatre nouveaux cas de patients atteints de GW (deux hommes, deux femmes), âges de 49 a 59 ans au moment du diagnostic, presentant des lesions dorsales prevertebrales, localisees principalement a droite, ass...
#1David M HansellH-Index: 6
#2David A LynchH-Index: 5
Last. Alexander A BankierH-Index: 5
view all 4 authors...
1 CitationsSource