Mortality after Fluid Bolus in African Children with Severe Infection

The role of fluid resuscitation in the treatment of children with shock and life-threatening infections who live in resource-limited settings is not established.We randomly assigned children with severe febrile illness and impaired perfusion to receive boluses of 20 to 40 ml of 5% albumin solution (albumin-bolus group) or 0.9% saline solution (saline-bolus group) per kilogram of body weight or no bolus (control group) at the time of admission to...