Multifunctional biodegradable terbium-doped calcium phosphate nanoparticles: facile preparation, pH-sensitive drug release and in vitro bioimaging

A facile room-temperature solution method for the preparation of biodegradable terbium (Tb)-doped calcium phosphate (CaP) nanoparticles is reported. The morphology, chemical composition, photoluminescence (PL), drug loading/release, cell viability and in vitro bioimaging of as-prepared Tb-CaP nanoparticles are investigated. The Tb-CaP nanoparticles consist of an amorphous phase. The PL of Tb-CaP nanoparticles with a strong emission at 544 nm is...