Original paper
Multi-responses extraction optimization based on response surface methodology combined with polarity switching HPLC–MS/MS for the simultaneous quantitation of 11 compounds in Cortex Fraxini: Application to four species of Cortex Fraxini and its 3 confusable species
Volume: 91, Pages: 210 - 221
Published: Mar 1, 2014
Abstract
A novel polarity switching high performance liquid chromatography–electrospray ionization tandem mass spectrometry (HPLC–ESI-MS/MS) approach combining optimization of extraction condition by response surface methodology (RSM) was developed for the simultaneous quantitative analysis of 11 compounds in Cortex Fraxini, a commonly used traditional Chinese medicine. The ultrasonic extraction conditions of the 11 analytes including sample quantity,...
Paper Details
Title
Multi-responses extraction optimization based on response surface methodology combined with polarity switching HPLC–MS/MS for the simultaneous quantitation of 11 compounds in Cortex Fraxini: Application to four species of Cortex Fraxini and its 3 confusable species
Published Date
Mar 1, 2014
Volume
91
Pages
210 - 221
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