Early PSA level decline is an independent predictor of biochemical and clinical control for salvage postprostatectomy radiotherapy

To improve the early detection of responders to salvage external beam radiotherapy (RT) after radical prostatectomy (RP).Between 2002 and 2007, in a single institution, 136 consecutive patients received salvage RT to a dose of 66 Gy without androgen-deprivation therapy after RP for a rising prostate-specific antigen (PSA) level. PSA measurements were systematically performed before RT (PSART), at the fifth week of RT (PSA5), and in the follow-up...