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Original paper

The frpB1 gene of Helicobacter pylori is regulated by iron and encodes a membrane protein capable of binding haem and haemoglobin

Volume: 586, Issue: 6, Pages: 875 - 879
Published: Feb 20, 2012
Abstract
FrpB1 is a novel membrane protein of Helicobacter pylori that is capable of binding both haem and haemoglobin but consistently shows more affinity for haem. The mRNA levels of frpB1 were repressed by iron and lightly modulated by haem or haemoglobin. The overexpression of the frpB1 gene supported cellular growth when haem or haemoglobin were supplied as the only iron source. Three‐dimensional modelling revealed the presence of motifs necessary...
Paper Details
Title
The frpB1 gene of Helicobacter pylori is regulated by iron and encodes a membrane protein capable of binding haem and haemoglobin
Published Date
Feb 20, 2012
Volume
586
Issue
6
Pages
875 - 879
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