Small molecule Me6TREN mobilizes hematopoietic stem/progenitor cells by activating MMP-9 expression and disrupting SDF-1/CXCR4 axis
Abstract
Key Points The small molecule Me6TREN is a new potent and efficacious mobilizing agent of HSPCs and works more effectively than G-CSF or AMD3100. Me6 mobilizes murine HSPCs and functions by upregulating MMP-9 expression and disrupting the SDF-1α/CXCR4...
Paper Details
Title
Small molecule Me6TREN mobilizes hematopoietic stem/progenitor cells by activating MMP-9 expression and disrupting SDF-1/CXCR4 axis
Published Date
Jan 16, 2014
Journal
Volume
123
Issue
3
Pages
428 - 441
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