Cassane- and Norcassane-Type Diterpenes from Caesalpinia crista of Indonesia and Their Antimalarial Activity against the Growth of Plasmodium falciparum
Abstract
The CH2Cl2 extract of the seed kernels of Caesalpinia crista, which exhibited promising antimalarial activity against Plasmodium berghei-infected mice in vivo, was examined and resulted in the isolation of seven new furanocassane-type diterpenes [caesalpinins C-G (1-5) and norcaesalpinins D and E (6, 7)] together with norcaesalpinins A-C (8-10) and 11 known compounds (norcaesalpinins A-C, 2-acetoxy-3-deacetoxycaesaldekarin e, caesalmin B,...
Paper Details
Title
Cassane- and Norcassane-Type Diterpenes from Caesalpinia crista of Indonesia and Their Antimalarial Activity against the Growth of Plasmodium falciparum
Published Date
Apr 21, 2005
Journal
Volume
68
Issue
5
Pages
706 - 710
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