Candidate mechanisms for chemotherapy-induced cognitive changes
Abstract
The mechanism(s) for chemotherapy-induced cognitive changes are largely unknown; however, several candidate mechanisms have been identified. We suggest that shared genetic risk factors for the development of cancer and cognitive problems, including low-efficiency efflux pumps, deficits in DNA-repair mechanisms and/or a deregulated immune response, coupled with the effect of chemotherapy on these systems, might contribute to cognitive decline in...
Paper Details
Title
Candidate mechanisms for chemotherapy-induced cognitive changes
Published Date
Mar 1, 2007
Journal
Volume
7
Issue
3
Pages
192 - 201
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