Comparative (Q)SAR analysis of benzodiazepine derivatives with different biological activity

211 compounds containing a benzodiazepine moiety (BZD) and belonging to 4 groups of different biological activity (H - inhibitors of reverse transcriptase of HIV-I virus, A - antiarrhythmic agents, G - ligands of benzodiazepine receptor in GABAergic system and C - cholecystokinin receptor antagonists) were subjected to structure–activity relationship (SAR) analysis. SAR investigations of all 211 BZD were based on Discriminant Function Analysis...