Original paper

miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β

Volume: 6, Issue: 1
Published: Apr 15, 2015
Abstract
As patient survival drops precipitously from early-stage cancers to late-stage and metastatic cancers, microRNAs that promote relapse and metastasis can serve as prognostic and predictive markers as well as therapeutic targets for chemoprevention. Here we show that miR-1269a promotes colorectal cancer (CRC) metastasis and forms a positive feedback loop with TGF-β signalling. miR-1269a is upregulated in late-stage CRCs, and long-term monitoring...
Paper Details
Title
miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β
Published Date
Apr 15, 2015
Volume
6
Issue
1
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