Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke

Among patients with acute ischemic stroke due to occlusions in the proximal anterior intracranial circulation, less than 40% regain functional independence when treated with intravenous tissue plasminogen activator (t-PA) alone. Thrombectomy with the use of a stent retriever, in addition to intravenous t-PA, increases reperfusion rates and may improve long-term functional outcome.We randomly assigned eligible patients with stroke who were...