Influence of lactose carrier particle size on the aerosol performance of budesonide from a dry powder inhaler
Abstract
The purpose of this study was to evaluate the effect of carrier particle size on properties of dry powder and its effect on dry powder inhaler (DPI) performance. Commercial α-lactose-monohydrate, a commonly used carrier in DPI formulations, was carefully sieved to obtain different lactose size fractions, namely Lac A (90–125 μm), Lac B (63–90 μm), Lac C (45–63 μm), Lac D (20–45 μm), and Lac E (< 20 μm). The lactose samples were analysed in terms...
Paper Details
Title
Influence of lactose carrier particle size on the aerosol performance of budesonide from a dry powder inhaler
Published Date
Sep 1, 2012
Journal
Volume
227
Pages
74 - 85
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