Internal medicine

Phenotype

Tetralogy of Fallot

Antibiotics

Bacteria

Biology

Microbiology

Gene

Endocarditis

Chemistry

Immunology

Sepsis

Staphylococcus

Staphylococcus aureus

Deletion syndrome

Heart disease

Staphylococcus lugdunensis

Genetics

Biochemistry

Medicine

Immune system

Internal Medicine

A 27-year-old woman visited our hospital because of high fever. She had been diagnosed as 22q11.2 deletion syndrome (22q11.2DS) due to her cardiac history (tetralogy of Fallot), thymic hypoplasia and 22q11.2 deletion. She had a normal CD4/CD8 ratio, a slightly decreased lymphocyte count and normal serum immunoglobulin levels. Blood cultures were positive for Staphylococcus lugdunensis (S. lugdunensis). Infection route of S. lugdunensis in this case was unclear. The patient was successfully treated with several intravenous antibiotics. Infection should be considered when managing patients with 22q.11.2DS. regardless of whether their immune system is impaired.

Successful Treatment of Sepsis Caused by Staphylococcus lugdunensis in an Adult with 22q11.2 Deletion Syndrome