Correlation between dose-volume constraints and late rectum bleeding in patients treated for prostate cancer at dose between 70 and 76 Gy

Purpose: To search for possible correlation between late rectal bleeding and dose-volume information taken from 3D treatment planning. Materials and Methods: Data from three institutions were included in current analysis; 3D treatment planning (including DVH) and clinical data of 364 patients treated for prostate cancer were collected. Patients with large air/fecal rectum content in the planning CT were excluded from the analysis(cut-off equal...