Review paper
Advances in human antiglomerular basement membrane disease
Abstract
Antiglomerular basement membrane (anti-GBM) disease is an autoimmune disorder that mostly presents as raised titers of antibodies against the GBM, rapidly progressive glomerulonephritis and pulmonary hemorrhage. The disease is caused by antibodies against noncollagenous domain of α3 chain of type IV collagen, which contains the epitopes E(A) and E(B). The humoral and cellular immunity contributing to the initiation of anti-GBM disease has been...
Paper Details
Title
Advances in human antiglomerular basement membrane disease
Published Date
Jul 19, 2011
Journal
Volume
7
Issue
12
Pages
697 - 705
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Notes
History