Epigenetic Targeting of Ovarian Cancer Stem Cells
Abstract
Emerging results indicate that cancer stem-like cells contribute to chemoresistance and poor clinical outcomes in many cancers, including ovarian cancer. As epigenetic regulators play a major role in the control of normal stem cell differentiation, epigenetics may offer a useful arena to develop strategies to target cancer stem-like cells. Epigenetic aberrations, especially DNA methylation, silence tumor-suppressor and differentiation-associated...
Paper Details
Title
Epigenetic Targeting of Ovarian Cancer Stem Cells
Published Date
Sep 1, 2014
Journal
Volume
74
Issue
17
Pages
4922 - 4936
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Notes
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