FDG PET/CT in oncology: "raising the bar".

Published on Jul 1, 2010in Clinical Radiology2.118
· DOI :10.1016/J.CRAD.2010.01.003
C.N. Patel1
Estimated H-index: 1
(Churchill Hospital),
Chirag Patel13
Estimated H-index: 13
(Churchill Hospital)
+ 1 AuthorsAndrew Scarsbrook29
Estimated H-index: 29
(Leeds Teaching Hospitals NHS Trust)
Integrated positron-emission tomography/computed tomography (PET/CT) with 2-[ 18 F]-fluoro-2-deoxy- d- glucose (FDG) has revolutionized oncological imaging in recent years and now has a firmly established role in a variety of tumour types. There have been simultaneous step-wise advances in scanner technology, which are yet to be exploited to their full potential in clinical practice. This article will review these technological developments and explore how refinements in imaging protocols can further improve the accuracy and efficacy of PET/CT in oncology. The promises, and limitations, of emerging oncological applications of FDG PET/CT in radiotherapy planning and therapy response assessment will be explored. Potential future developments, including the use of FDG PET probes in oncological surgery, advanced data analysis techniques, and the prospect of integrated PET/magnetic resonance imaging (PET/MRI) will be highlighted.
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